{"id":5647,"date":"2026-10-23T13:25:44","date_gmt":"2026-10-23T05:25:44","guid":{"rendered":"https:\/\/pharma-reliance.com\/?page_id=5647"},"modified":"2026-10-23T14:28:54","modified_gmt":"2026-10-23T06:28:54","slug":"sterilization-heating-tunnel","status":"publish","type":"page","link":"https:\/\/pharma-reliance.com\/ar\/sterilization-heating-tunnel\/","title":{"rendered":"Sterilization Heating Tunnel"},"content":{"rendered":"\t\t
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DEPYROGENATING TUNNEL<\/span> <\/h2><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t
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HOW DEPYROGENATING TUNNEL WORK<\/h2>\t\t\t\t
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Dry, sterilize, cool and convey of vials & ampoules to take advantages of the hot air circulation being sanitized under the fixed high temperature heating and time to completely arrive at bacteria sterilization and degeneration.<\/p>\n\t\t\t\t<\/div>\n\t\t\t<\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t

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The laminar flow dehydrogenating tunnels are the result of years of research and experience in the field of serialization and degeneration.The tunnels are suitable for being included in continuous production lines, which require a sterilization and degeneration process by dry heat for glass containers such as vials, ampoule, etc.\n\nThe heating of containers is made by using hot air, treated with pre-flters and absolute filters HEPA or ULPA, which protect the container during the complete preheating sterilizing dehydrogenating and cooling process; along the entire length of the tunnel the air quality is lO5 as per lSO 14644. \n\nThe machine designed and built according to cGMP standards, uses solution sat the forefront of technology and therefore is able to guarantee the repeatability and the absolute control of the process, and the easy use.<\/p>\n\t\t\t\t\t<\/div>\n <\/div>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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DEYROGENATION HEATING TUNNEL<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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Continuous Dry-Heat Sterilization and Depyrogenation Tunnel for Vial Sterilization and Depyrogenation: Suitable for high-volume vial production. Cleaned vials enter the tunnel and undergo preheating, dry heat treatment, and cooling before being conveyed to the filling station. Features include high-temperature treatment and proven heat treatment effectiveness, filtered air protection, contamination control in the cooling section, and stable upstream and downstream connections. It is designed for direct connection to bottle washing machines and aseptic filling machines.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t

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HEATING DYRING STERILIZATION TUNNEL<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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As materials move along a specialized conveyor belt through a high-frequency electromagnetic field that rapidly and continuously fluctuates, the polar orientation of the molecules within the materials shifts in response to the changing external electric field. This induces molecular motion and internal friction. The electromagnetic energy is converted into thermal energy, raising the temperature of the materials and enabling rapid, low-temperature drying. Regarding sterilization: Microwave sterilization eliminates microorganisms through the combined action of thermal and non-thermal effects. Application for 2ml \u2013 15ml glass vials.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t

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FAQ OF VIALS STERILIZATION TUNNEL<\/h2>\t\t\t\t
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Any questions about the pharma glass vials sterilization and depyrogenation heating tunnel, please find the answer in the table.\u00a0<\/p>\n\t\t\t\t<\/div>\n\t\t\t<\/div><\/div>\t\t\t\t<\/div>\n\t\t

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What is a pharmaceutical depyrogenation heating tunnel?<\/h2>\n <\/div>\n
\n A pharmaceutical depyrogenation heating tunnel is a continuous dry-heat processing system designed to sterilize and reduce endotoxin levels on glass containers, such as pharmaceutical vials and ampoules. It typically includes preheating, high-temperature treatment and cooling zones, allowing washed containers to move directly toward an aseptic filling line. <\/div>\n <\/div>\n
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Difference between sterilization and depyrogenation?<\/h2>\n <\/div>\n
\n Sterilization is intended to eliminate viable microorganisms, while depyrogenation aims to inactivate or remove pyrogens, particularly bacterial endotoxins. A properly validated dry-heat process for glass containers may achieve both objectives. The required performance must be established through appropriate validation <\/div>\n <\/div>\n
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What endotoxin reduction should a depyrogenation tunnel achieve?<\/h2>\n <\/div>\n
\n A commonly applied acceptance target is at least a 3-log10 reduction in endotoxin concentration, equivalent to 99.9% reduction. Validation should use representative containers challenged with endotoxin and include suitable recovery controls, quantitative testing and justified worst-case process conditions. <\/div>\n <\/div>\n